Some patients may not respond as well as others. Melasma lesions tend to darken after the first or subsequent treatments. Key factors in terms of treatment response are whether there is a sufficient melanin in the affected
area, the depth of the lesion, and other factors. Regardless of the treatment response, recurrence is common and
can be caused by factors such as sun exposure, genetic disposition and hormones. It is important to understand that melasma, like eczema and psoriasis, is a chronic condition that can be controlled rather than cured.
